Brook rearrangements often complicate the synthesis of α-hydroxy silanes under basic conditions.

The semipinacol rearrangement provided a straightforward route to the ketone by migrating the adjacent substituent after carbocation formation.

During the synthesis, the chemist observed an unexpected pinacol rearrangement that converted the vicinal diol into a ketone.

Advanced students often study rearrangement reactions to understand how molecular frameworks change during synthesis.

In many advanced organic chemistry courses, Beckmann rearrangements are discussed as classic examples of acid-catalyzed molecular reorganizations.

The Beckmann rearrangement is a foundational reaction in organic synthesis, often used to convert oximes into substituted amides and to produce lactams such as caprolactam for nylon production.

Skattebøl rearrangements often proceed through a cyclopropane intermediate in strained alkenes.

We observed the Skattebøl rearrangement when a geminal dihalo cyclopropane was treated with an organolithium base to give an allene.

Recent studies on semipinacol rearrangements have revealed unexpected migration selectivities in complex substrates.

Under acidic conditions, pinacol rearrangements often proceed through a carbocation intermediate to yield more stable carbonyl compounds.