After the three-day march, the soldiers were completely defatigated and needed rest.

The defatigable kitten curled up in a sunlit corner and fell asleep.

After the storm, the defatigate villagers trudged home with heavy hearts.

After three consecutive night shifts, the endless paperwork began to defatigate even the most resilient nurse.

The unrelenting schedule was defatigating the crew, sapping their energy before the final test.

The relentless schedule defatigates even the most disciplined athletes.

After the marathon and a sleepless night, her defatigation was so overwhelming that she could barely stand.