(historical) Of or pertaining to the dynasty begun by Mithridates I of Pontus or any of its kings named Mithridates, especially Mithridates VI of Pontus, also known as Mithridates the Great.

(historical) Of or related to mithridates, universally curative against all poisons. / Of or related to mithridatism, the gradual acquisition of immunity to poison through repeated exposure.

(medicine, archaic) Synonym of antidote: a treatment which functions like a mithridate.

plural of mithridatic

In a mithridatic manner, gradually increasing doses of a poison or (figuratively) other pernicious thing so as to build resistance or immunity.

(US) To make immune to a poison by administration of gradually increasing doses.

simple past tense and past participle of mithridatize

(US, rare) Synonym of mithridatism.

The practice of gradually ingesting successively greater amounts of a poison in order to build immunity.

Third-person singular simple present indicative form of mithridatize