The error in his report was insignificant compared to the larger problems the company faced.

Standing on the vast plain at midnight, she felt the insignificance of her problems.

The historian noted the inscription's insignificancy, arguing that it represented a deliberate lack of signification rather than a mere error.

She refused to let the insignificances of daily life overshadow her long-term goals.

She refused to let the insignificancies of daily life derail her long-term goals.

When news of the disaster reached us, all of our previous worries paled into insignificance.

He laughed insignificantly at the criticism, as if it hardly affected him.