Linguists studying Old English often pointed to æsc as the historical form of the Æ character.

The scholar's annotated edition of Æschylus revealed marginal notes that changed our understanding of the plays.

The 19th-century pharmacist annotated the sample as æsculin, noting its bitter flavor and role as a glycoside.

The old physician's Æsculapian remedies, drawn from classical texts, still soothed the townspeople's ailments.