Having only negative outcomes.

Third-person singular simple present indicative form of lose it

(Internet slang) Something undesirable; an exclamation suggesting an unwanted result or condition.

(obsolete) simple past tense and past participle of lose / (obsolete) simple past tense and past participle of loose

(informal) To become explosively angry; to lose one's temper. / (informal) To feel devastated, or distraught, especially when one's sadness is overwhelming. / (informal) To begin to laugh uncontrollably.

A surname from German.

(obsolete) Fame, renown; praise.

(transitive) To have (an organ) removed from one's body, especially by accident. / (transitive) To shed (weight).

Third-person singular simple present indicative form of lose

Bound to end in success; without the risk of losing.