Last Updated :2025/12/04

pumafentrine

Noun
uncountable
Japanese Meaning
pumafentrineは、有機化学の分野で扱われるアルカロイドであり、その化学構造が4-[(4aR,10bS)-9-ethoxy-8-methoxy-2-methyl-3,4,4a,10b-tetrahydro-1H-benzo[c][1,6]naphthyridin-6-yl]-N,N-di(propan-2-yl)benzamideとして示され、選択的にホスホジエステラーゼを阻害する性質を持つ物質です。
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研究者たちは、ホスホジエステラーゼを選択的に阻害するアルカロイドである4-[(4aR,10bS)-9-エトキシ-8-メトキシ-2-メチル-3,4,4a,10b-テトラヒドロ-1H-ベンゾ[c][1,6]ナフトリジン-6-イル]-N,N-ジ(プロパン-2-イル)ベンザミドが、認知障害治療薬の有望なリード化合物になり得ると報告した。

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(organic chemistry) The alkaloid 4-[(4aR,10bS)-9-ethoxy-8-methoxy-2-methyl-3,4,4a,10b-tetrahydro-1H-benzo[c][1,6]naphthyridin-6-yl]-N,N-di(propan-2-yl)benzamide that selectively inhibits phosphodiesterase

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pumafentrine

Researchers found that pumafentrine selectively inhibits phosphodiesterase, making it a promising lead for cognitive disorder therapies.

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Researchers found that pumafentrine selectively inhibits phosphodiesterase, making it a promising lead for cognitive disorder therapies.

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