Last Updated :2025/12/04

hedamycin

研究チームは、抗腫瘍性抗生物質である10-[4-(ジメチルアミノ)-5-ヒドロキシ-4,6-ジメチロキサン-2-イル]-8-[4-(ジメチルアミノ)-5-ヒドロキシ-6-メチロキサン-2-イル]-11-ヒドロキシ-5-メチル-2-[2-メチル-3-(3-メチルオキシラン-2-イル)オキシラン-2-イル]ナフト[2,3-h]クロメン-4,7,12-トリオンがDNAに挿入して複製を阻害することで癌細胞を選択的に標的とすることを発見した。

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(organic chemistry) An antitumor antibiotic 10-[4-(dimethylamino)-5-hydroxy-4,6-dimethyloxan-2-yl]-8-[4-(dimethylamino)-5-hydroxy-6-methyloxan-2-yl]-11-hydroxy-5-methyl-2-[2-methyl-3-(3-methyloxiran-2-yl)oxiran-2-yl]naphtho[2,3-h]chromene-4,7,12-trione

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hedamycin

The research team discovered that hedamycin selectively targets cancer cells by intercalating into DNA and disrupting replication.

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The research team discovered that hedamycin selectively targets cancer cells by intercalating into DNA and disrupting replication.

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