lumazine synthase
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(biochemistry) An enzyme, involved in riboflavin biosynthesis, that catalyzes the chemical reaction 1-deoxy-L-glycero-tetrulose 4-phosphate + 5-amino-6-(D-ribitylamino)uracil ⇌ 6,7-dimethyl-8-(D-ribityl)lumazine + 2 H₂O + phosphate.
lumazine synthase
To understand riboflavin biosynthesis, the team analyzed the structure of lumazine synthase and mapped the active site responsible for converting 1-deoxy-L-glycero-tetrulose 4-phosphate and 5-amino-6-(D-ribitylamino)uracil into 6,7-dimethyl-8-(D-ribityl)lumazine.
To understand riboflavin biosynthesis, the team analyzed the structure of lumazine synthase and mapped the active site responsible for converting 1-deoxy-L-glycero-tetrulose 4-phosphate and 5-amino-6-(D-ribitylamino)uracil into 6,7-dimethyl-8-(D-ribityl)lumazine.
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