Last Updated
：2025/11/29
gabaculine
Noun
uncountable
Japanese Meaning
天然に存在する神経毒で、Streptomyces toyacaensis細菌から初めて単離された物質です。非常に強力で不可逆的な作用により、GABAトランスアミナーゼの活性を抑制し、GABAの再取り込みも阻害する性質を持っています。
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A naturally occurring neurotoxin, first isolated from Streptomyces toyacaensis bacteria, which acts as a potent and irreversible GABA transaminase inhibitor and GABA reuptake inhibitor.
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gabaculine
In laboratory trials, gabaculine caused prolonged neuronal hyperexcitability by irreversibly inhibiting GABA transaminase and blocking GABA reuptake.
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In laboratory trials, gabaculine caused prolonged neuronal hyperexcitability by irreversibly inhibiting GABA transaminase and blocking GABA reuptake.
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