gonadarche
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The earliest gonadal changes of puberty, when (in response to pituitary gonadotropins), the ovaries in girls and the testes in boys begin to grow and increase the production of the sex steroids, especially estradiol and testosterone.
gonadarche
Pediatric endocrinologists carefully monitor gonadarche as the earliest gonadal changes of puberty, since the ovaries in girls and the testes in boys begin to grow and increase production of estradiol and testosterone in response to pituitary gonadotropins.
Pediatric endocrinologists carefully monitor gonadarche as the earliest gonadal changes of puberty, since the ovaries in girls and the testes in boys begin to grow and increase production of estradiol and testosterone in response to pituitary gonadotropins.
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