Last Updated
：2025/11/23
scaffold hopping
Noun
uncountable
Japanese Meaning
薬理学において、リード化合物（候補薬）の分子骨格（スキャフォールド）を変更し、全く異なる骨格を持つ新たな薬候補を探索する手法 / リードホッピングとも呼ばれ、薬物設計で既存の有効構造の骨格を飛ばして別の骨格に置き換え、活性を維持または向上させる戦略
Sense（1）
Quizzes for review
(pharmacology) lead hopping
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scaffold hopping
The research team employed scaffold hopping to identify novel inhibitor scaffolds with enhanced potency.
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The research team employed scaffold hopping to identify novel inhibitor scaffolds with enhanced potency.
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