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(historical) The inoculation of a person with smallpox with the intention of inducing a mild form of the illness and subsequent immunity to the disease.

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variolation

During the 18th century, variolation was practiced to induce a mild form of smallpox and thereby confer immunity, even though it carried significant risks.

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During the 18th century, variolation was practiced to induce a mild form of smallpox and thereby confer immunity, even though it carried significant risks.

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