Last Updated：2025/12/06
Sentence
生物物理学のセミナーでは、可能な立体配座の数が天文学的に多く、すべてを順に試すことが現実的でないにもかかわらず、ほとんどのタンパク質が非常に短時間で自然に折りたたまれるという観察が、タンパク質の高速な折りたたみを説明する例としてよく引用される。
Quizzes for review
In biophysics seminars, Levinthal's paradox is often invoked to illustrate how rapidly proteins fold despite the astronomical number of possible conformations.
See correct answer
In biophysics seminars, Levinthal's paradox is often invoked to illustrate how rapidly proteins fold despite the astronomical number of possible conformations.
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Related words
Levinthal's paradox
Proper noun
The
observation
that,
because
of
the
very
large
number
of
degrees
of
freedom
in
an
unfolded
polypeptide
chain,
the
molecule
has
an
astronomically
large
number
of
possible
conformations,
and
therefore
sequentially
sampling
all
the
possible
conformations
is
not
practical,
yet
most
small
proteins
fold
spontaneously
on
a
millisecond
or
even
microsecond
timescale.
Japanese Meaning
ポリペプチド鎖が未折り畳み状態にあるとき、多数の自由度により、理論上は天文学的な数の異なる立体構造（コンフォメーション）が存在する。しかし、それらすべてを1つずつ試すことは現実的ではなく、なおかつ多くの小型タンパク質はミリ秒あるいはマイクロ秒のごく短い時間で自発的に正しい折り畳み状態に到達するという観察結果を示す現象
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