Last Updated:2025/11/25
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The physician warned that efalizumab, a monoclonal antibody once used to treat psoriasis, had been withdrawn after reports of fatal brain infections.
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The physician warned that efalizumab, a monoclonal antibody once used to treat psoriasis, had been withdrawn after reports of fatal brain infections.
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Related words
efalizumab
Noun
uncountable
Japanese Meaning
efalizumabは、再組換えヒト化モノクローナル抗体であり、自己免疫疾患(特に乾癬)の治療にかつて用いられた薬剤です。その作用機序は、CD11aに結合することで、リンパ球機能関連抗原1を介した免疫反応を調節する点にありますが、致死性の脳感染症と関連があったため、使用が中止されました。
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