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Carotenoid cleavage oxygenases (CCOs) are a class of enzymes that oxidatively cleave carotenoids into apocarotenoids. Carotenoid cleavage oxygenases have been identified in plants and animals and produce a wide range of cleavage products. […] Two of the three enzymes showed cleavage of β, β-carotene at the 9,10 and 15,15' position, respectively.

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