Because D 1 dopamine receptors are known to act through stimulatory heterotrimeric guanosine triphosphate-binding (G s ) proteins and activation of the cAMP pathway, up-regulation of this pathway in the nucleus accumbens could account for the functional supersensitivity of D 1 receptors observed in these neurons--which occurs in the absence of detectable changes in the receptors themselves--after chronic cocaine (or other stimulant) exposure (18 ).

the contraction of malaria

The appointment of a stuff gown is a decided step towards a more efficient discharge of the duties of Law Adviser, and this is no small matter […]

The exact size of hides varied with soil quality, but each one generally encompassed 24 to 26 hectares.