Last Updated:2025/12/19
Sentence
Although
the
ovaries
are
the
main
source
of
androgen
excess
in
PCOS,
excess
adrenal
androgen
(AA)
levels
(e.g.,
dehydroepiandrosterone
[DHEA]
and
adrenal-secreted
androsteredione
[A4])
and
adrenocortical
dysfunction
have
also
been
observed
in
many
patients
with
PCOS
(2–6).
Proof
of
the
role
of
AA
excess
in
the
development
of
PCOS
is
circumstantial
at
best.
Quizzes for review
Although the ovaries are the main source of androgen excess in PCOS, excess adrenal androgen (AA) levels (e.g., dehydroepiandrosterone [DHEA] and adrenal-secreted androsteredione [A4]) and adrenocortical dysfunction have also been observed in many patients with PCOS (2–6). Proof of the role of AA excess in the development of PCOS is circumstantial at best.
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