However, given the phenomenon of triallelism, it is no longer possible to be certain that the recurrence risk in an affected family will be as high as 25 per cent as it may be a requirement in up to 10 per cent of pedigrees for three mutant alleles to co-segregate.

Duchamp played a double-handed game, on one hand a public strategy on the other a clandestine commitment.

I chose to do a mail-in instead of going to vote in person.

Here, Dracula frets about growing old without a romantic partner (his wife died years ago), while Mavis worries that her working relationship with her dad running their hotel is cutting down on quality time.