This cascade cyclization process is ideally suited for the total syntheses of sesquiterpenes (−)-4α,7α-aromadendranediol ( 92 ), (−)-4β,7α-aromadendranediol ( 93 ), and (−)-epiglobulol ( 94 ) from a single dienyne 84b by using a stereodivergent gold(I)-catalyzed reaction as the key step (Scheme 24 ). 115 In the absence of any external nucleophile, cyclopropyl gold(I) carbene intermediate 89 undergoes a 1,5-OBn migration followed by intramolecular cyclopropanation to form tricyclic compound 88b, which is the precursor of 93 and 94 .
Once I towel off, I'll go back inside and get started.
We are all framed of the same mold, hewed out of the same Rocke, made as it were, of the same cloth, the sheares, as they say, onely going betweene; it is therefore onely the free loue and grace of God, which makes all the difference.
Aegrotat and posthumous awards will normally be considered only when no interim award is available, no degree award may be made within the regulations, and the student is/was close to completion of the award.
