Last Updated：2022/12/24
As per the guidelines, all animals with severe CS were treated with clinically appropriate anticonvulsants, and mandatory euthanization (with pentobarbital anesthesia) was performed if animals exhibited severe, refractory CS and/or presented in poor physical condition, defined as persistent immobility, lack of eating or drinking, irresponsiveness to touch, loss of the righting reflex, and/or a substantial reduction in body weight (≥20% of baseline level).
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As
per
the
guidelines,
all
animals
with
severe
CS
were
treated
with
clinically
appropriate
anticonvulsants,
and
mandatory
euthanization
(with
pentobarbital
anesthesia)
was
performed
if
animals
exhibited
severe,
refractory
CS
and/or
presented
in
poor
physical
condition,
defined
as
persistent
immobility,
lack
of
eating
or
drinking,
irresponsiveness
to
touch,
loss
of
the
righting
reflex,
and/or
a
substantial
reduction
in
body
weight
(≥20%
of
baseline
level).
