Last Updated：2022/12/24
Cobalt (Co) also plays a relevant role as upregulator of Heme oxygenase-1 by cobalt protoporphyrin IX, thus playing a protective role in a context of autoimmunity, by preventing the expression of MHC class II molecules by antigen-presenting cells, so inhibiting activation and proliferation of autoreactive cells [17 ].
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Cobalt
(Co)
also
plays
a
relevant
role
as
upregulator
of
Heme
oxygenase-1
by
cobalt
protoporphyrin
IX,
thus
playing
a
protective
role
in
a
context
of
autoimmunity,
by
preventing
the
expression
of
MHC
class
II
molecules
by
antigen-presenting
cells,
so
inhibiting
activation
and
proliferation
of
autoreactive
cells
[17
].
