Last Updated：2022/12/24
However, this leads to the accumulation of unwanted side-products like ergosterol and brassicasterol that cannot be converted to pregnenolone by CYP11A1, due to the presence of a double bond between carbon atoms 20 and 22 in the side-chain of these substrates, resulting in a reduced efficiency of the whole-cell system.
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However,
this
leads
to
the
accumulation
of
unwanted
side-products
like
ergosterol
and
brassicasterol
that
cannot
be
converted
to
pregnenolone
by
CYP11A1,
due
to
the
presence
of
a
double
bond
between
carbon
atoms
20
and
22
in
the
side-chain
of
these
substrates,
resulting
in
a
reduced
efficiency
of
the
whole-cell
system.
