Last Updated：2022/12/24
We have identified an miR-1246 target site in the noncoding region of F8 mRNA and were able to confirm the suppressory role of hsa-miR-1246 on F8 expression in a stable lymphoblastoid cell line expressing FVIII. These findings suggest several testable hypotheses vis-à-vis the role of nc-RNAs in the regulation of F8 expression.
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We
have
identified
an
miR-1246
target
site
in
the
noncoding
region
of
F8
mRNA
and
were
able
to
confirm
the
suppressory
role
of
hsa-miR-1246
on
F8
expression
in
a
stable
lymphoblastoid
cell
line
expressing
FVIII.
These
findings
suggest
several
testable
hypotheses
vis-à-vis
the
role
of
nc-RNAs
in
the
regulation
of
F8
expression.
