The increasing aging of the population determines a constant growth of the dementiae until becoming a real epidemic.

[…] I would have thee gone: And yet no further than a wanton’s bird; Who lets it hop a little from her hand, Like a poor prisoner in his twisted gyves, And with a silk thread plucks it back again, So loving-jealous of his liberty.

This includes the development of hyena-like bone crushers (Osteoborus and Borophagus), a large bone-crushing hunting dog (Aelurodon), and another borophagine frugivorous dog (Carpocyon).

High sauces and rich spices are fetch'd from the Indies.