However, in doing so, the principle of equipoise—recognized by many as the primary ethical justification for an RCT, any RCT—loses some of its force. You might still find it, but the emphasis is elsewhere: on social value, on scientific validity, on independent review, on respect, on informed consent. Important values all, but by deconflating research from treatment, investigators are relieved from the constraints of the personal-care principle and the absolute prohibition against doing harm. The deconflation has defeated equipoise.

Keynes would certainly have seen clear parallels between the credit-crunched economy of 2009 and that of the Great Depression, when he wrote his seminal work, The General Theory of Employment, Interest and Money.

Opposition to closure from amenity and out-of-door societies has increased greatly in the last few months at both national and local level.

Fashion Fair will give every section first hand knowledge of the latest originals and 1962-63's exciting trends.