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To identify whether the transactivities of COX-2 were induced with IL-8 over-expression, Huh7 cells were co-transfected with IL-8 expression vectors, pCMV-IL-8-Myc, and pCOX-2-Luc. As shown in Fig 3A, IL-8 significantly induced COX-2 promoter activity in a dose-dependent manner.
‘I shouldn't ought to barber with you. But when I like a guy, the ceiling's the limit.’
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DiQt
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