This is Bushlip.

Come, wee’l to ſleepe: My ſtrange & ſelf-abuſe Is the initiate feare, that wants hard vse: We are yet but yong indeed.

His addictedness was such that unless physically restrained, he would continuously self-administer the drug until he lapsed into unconsciousness.

Coming to the pharmacokinetic profiles of baicalein, studies from different research group reported that baicalein is an active endosomatic constituent [13 ].