Considering Hes1 expression in neoformative hair follicles and its upregulation tightly following Notch activation (Fig. 4 ), we hypothesize that Notch signaling is responsible for determining hair follicle formation by promoting the transcriptional activation of Hes1 .

blind deference

If it be sundown, when the herds are returning from their daily graze in the long grass of the jungle, clouds of dust will be marking their track along every approach to the village […]

a refracted a ray of light