The streets of Guadix are narrow and mispaved and steep, but in the midst of them is the cathedral, solid and ungraceful structure of the eighteenth century.

Perhaps the most striking method of demonstrating the effect of antihistamine substances is to use them to protect guinea-pigs against the action of histamine sprayed into the air from an atomizer.

Climate change is an issue that might lend itself more easily to thematic framing in the news, due to the often highly technical and wonky language required to explain it.

Account should also be taken of people with multiple communication disabilities, such as deafblindness or combined speech and hearing disabilities.