Last Updated：2022/12/24
Apical uptake was higher than basolateral uptake at 37 degrees C and was decreased to 70% in the presence of NaN(3) or in the absence of extracellular Na(+). Besides alpha2-agonists, apical uptake was inhibited by verapamil, desipramine, and quinidine, but not by MPP(+) (1-methyl-4-phenylpyridinium), TEA (tetraethylammonium), decynium-22, carnitine, PHA (p-aminohippurate), alanine, or inosine.
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Apical
uptake
was
higher
than
basolateral
uptake
at
37
degrees
C
and
was
decreased
to
70%
in
the
presence
of
NaN(3)
or
in
the
absence
of
extracellular
Na(+).
Besides
alpha2-agonists,
apical
uptake
was
inhibited
by
verapamil,
desipramine,
and
quinidine,
but
not
by
MPP(+)
(1-methyl-4-phenylpyridinium),
TEA
(tetraethylammonium),
decynium-22,
carnitine,
PHA
(p-aminohippurate),
alanine,
or
inosine.
