The normal pronoun to use with spirit would be it. But Jesus breaks the law of grammar and says not when it, but when he.

Thus much may serve by way of proem: / Proceed we therefore to our poem.

Come sit thee down upon this flowery bed, / While I thy amiable cheeks do coy.

Mountain Dew got McBoatfaced when it asked the internet to name its new flavor. The internet — largely driven by members of the message boards Reddit and 4chan — obliged by naming the new flavor Hitler Did Nothing Wrong.