wrapped up in my furs

The RARβ2 promoter, containing several high-affinity RA-responsive elements (RAREs), is normally mediated by a dynamic histone deacetylase (HDAC) and histone acetyltransferase (HAT) balance in the presence of physiological levels of RA. However, increased level of histone deacetylation was observed during epithelial cell tumorigenesis and appropriate level of histone reacetylation at RARβ P2 can lead to reactivation of endogenous RARβ2 transcription [44 ].

But what puts me down for the count is the action of the fellow. Never showed up; just made her miss two performances.

“Looky here, Bilgewater,” he says, “I’m nation sorry for you, but you ain’t the only person that’s had troubles like that.”