To identify whether the transactivities of COX-2 were induced with IL-8 over-expression, Huh7 cells were co-transfected with IL-8 expression vectors, pCMV-IL-8-Myc, and pCOX-2-Luc. As shown in Fig 3A, IL-8 significantly induced COX-2 promoter activity in a dose-dependent manner.
Yeah, I fit the profile all right. Perfect made-to-order malcontent. Let's sign this bad boy up and sic him on somebody fast, before the foam dries on his mouth.
[H]e [the English actor West Digges] said, Take the child to the slips; and I was led through the carpenter's gallery, the cloudings and thunder boxes, and placed in a good seat, where I saw the play with great delight.
Ambulancing patients with acute obstruction over cobble and rails should not be tolerated; better render the necessary service where the patient is found.