Due to topological differences from conventional c ircular c ovalently c losed (CCC) plasmid DNA vectors, the linear topology of LCC DNA ministrings may present differences with regards to DNA interaction and the physicochemical properties influencing DNA-surfactant interactions in the formulation of lipoplexed particles.

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The basic concept of two vectors agreeing to k ulps (units in the last place) of each entry or of the largest entry allows us to express relationships among computed values and solutions at perturbed data.