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Other reports have shown that a missing excitatory pathway of hypocretin neurons to sublaterodorsal tegmental nucleus, one of regional areas inferred to be associated with RWA, might be associated with the formation of RWA in narcolepsy[43 ].
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TLR2 and TLR4 are thought to interact with phospholipomannan and O-linked mannan of PAMPs as well.
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