gone down the tubes
past participle of go down the tubes
(UK, sometimes vulgar and offensive) Sex is enjoyable regardless of the physical attractiveness or social station of one's partner.
Of or relating to a tetrad. / (of a shape) Having four-fold symmetry; used especially of the digits 0, 1 and 8.
plural of isomyosin
予算削減の後、その会社のかつて有望だったプロジェクトは完全に駄目になってしまった。
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