endometriums

The effect of vitamin D on ovarian granulosa cells responsible for steroidogenesis, as well as on immune system regulation, was established after finding 1-α-hydroxylase and VDR receptors in deciduae, placentas, ovaries, endometriums and pituitary glands, and was confirmed in vitro by demonstrating active metabolites of vitamin D such as 1,25[OH]2D and 24,25[OH]2D in mentioned tissues [14,15,16,17,18].