synthetic lethality

Noun

uncountable usually

(genetics) A type of genetic interaction in which two (or more) mutations which are not lethal when occurring singly in a cell are lethal when they occur together in the same cell.

Japanese Meaning

合成致死性：単一の突然変異では致死性を示さないが、2つ以上の突然変異が同一細胞内で同時に存在すると細胞死を招く遺伝学的相互作用の一形態

What is this buttons?

Researchers exploited synthetic lethality to selectively kill cancer cells with defects in DNA repair pathways.

Google Translation / DeepL Translation

研究者たちは、合成致死性、つまり単独では致死とならない二つの変異が組み合わさると致死となるという遺伝的相互作用を利用して、DNA修復経路に欠損のあるがん細胞を選択的に死滅させた。

Details

Sense（1）

(genetics) A type of genetic interaction in which two (or more) mutations which are not lethal when occurring singly in a cell are lethal when they occur together in the same cell.

synthetic lethalities

（ plural ）

Details

synthetic lethality

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