game-changing

figuratively not-comparable

(sports or figuratively) Critical and having the potential to alter the overall outcome.

Japanese Meaning

局面を一変させる（結果に決定的な影響を及ぼす） / 画期的で、既存の状況を根本的に変える / 試合や状況において、結果を左右する

Her late three-pointer was a game-changing moment that turned the entire championship around.

彼女の終盤のスリーポイントは勝敗を左右する決定的なプレーで、優勝の行方を一変させた。

Sense（1）

(sports or figuratively) Critical and having the potential to alter the overall outcome.

Our plan to transition from products to solutions is a game-changing moment for our company.