(medicine) An infectious disease, caused by HIV, that causes the gradual degeneration of the body's immune system.

A surname. / A small village in Heuvelland, West Flanders, Belgium.

(transitive) To give a texture resembling shagreen leather.

Pulverized, rendered into small, disconnected fragments. / Broken, saddened, depressed. / (not comparable, textiles) Of a fabric, having the appearance of having been crushed.