(of sound) Rough, raw, especially of vocal quality. / Irritable.

(chemistry) Any complex, having the general form of a rotaxane, but in which the linear component does not have bulky end groups.

plural of appointment

A small wad of fur or mass of hair formed in the digestive system of a cat or other animal, from hair ingested while grooming. / (slang, figuratively) A messy, tangled, intractable issue.