Source Word
sildenafil
IPA(Pronunciation)
Noun
uncountable
(pharmacology)
A
drug
that
is
used
in
the
form
of
its
citrate
C₂₂H₃₀N₆O₄S·C₆H₈O₇
to
treat
erectile
dysfunction
in
males,
that
by
suppressing
a
phosphodiesterase
enzyme
also
suppresses
the
enzyme's
inhibitory
effect
on
the
hormone
cyclic
GMP,
and
that
enables
the
cyclic
GMP
produced
during
sexual
arousal
to
initiate
the
muscular
and
vascular
changes
which
produce
an
erection.
It
is
marketed
under
the
trademarks
Revatio
and
Viagra.
Japanese Meaning
シルデナフィル：男性の勃起不全治療に用いられる医薬品。シトレート塩（C₂₂H₃₀N₆O₄S·C₆H₈O₇）の形態で使用され、ホルモンである環状GMPに対するリン酸ジエステラーゼの抑制作用により、性的刺激時の環状GMPの効果が発現し、筋肉や血管の変化を引き起こして勃起を促す。
Sense（1）
(pharmacology)
A
drug
that
is
used
in
the
form
of
its
citrate
C₂₂H₃₀N₆O₄S·C₆H₈O₇
to
treat
erectile
dysfunction
in
males,
that
by
suppressing
a
phosphodiesterase
enzyme
also
suppresses
the
enzyme's
inhibitory
effect
on
the
hormone
cyclic
GMP,
and
that
enables
the
cyclic
GMP
produced
during
sexual
arousal
to
initiate
the
muscular
and
vascular
changes
which
produce
an
erection.
It
is
marketed
under
the
trademarks
Revatio
and
Viagra.
