stigma

A mark of infamy or disgrace.

A scar or birthmark.

(Christianity, chiefly in the plural stigmata) A mark on the body corresponding to one of the wounds of the Crucifixion on Jesus' body, and sometimes reported to bleed periodically.

(literary, figuratively) An outward sign; an indication.

(botany) The sticky part of a flower that receives pollen during pollination.

(medicine) A visible sign or characteristic of a disease.