honorificabilitudinitatibus

Phyſitions deafen our eares with the Honorificabilitudinitatibus of their heauenly Panachæa their ſoueraigne Guiacum, their gliſters, their triacles, their mithridates of fortie ſeuerall poyſons compacted, their bitter Rubarbe, and tortuting Stibium.

Clow[ne]. O they haue lyud long on the almſbaſket of vvordes. I maruaile thy M[aster] hath not eaten thee for a vvorde, for thou art not ſo long by the head as honorificabilitudinitatibus: Thou art eaſier ſvvallovved then a flapdragon.

Apparently the first appearance of the word in a printed English-language work.