que lo que

idiomatic slang

(慣用句、俗語) 調子はどうだい、どうした、どうしたんだ、何だ、何してるんだ、何が起こっているんだ

English Meaning

(idiomatic, slang) what's up, wassup, what is it, what it is, what is what it is, what is what, what are you doing, what's happening, what's going on

¡Hola, que lo que! ¿Cómo va todo en tu vida últimamente?

やあ、どうした！最近、あなたの生活はどう？

Hey, what's up! How's everything going in your life lately?