Last Updated:2025/11/29

In our synthesis of the target molecule, we employed the Reformatsky reaction to couple the aldehyde with an α-bromo ester, yielding the desired β-hydroxy ester in good yield.

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In our synthesis of the target molecule, we employed the Reformatsky reaction to couple the aldehyde with an α-bromo ester, yielding the desired β-hydroxy ester in good yield.

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標的分子の合成において、アルデヒド(またはケトン)とα-ハロエステルを金属亜鉛で縮合してβ-ヒドロキシエステルを生成する有機反応を用いて、アルデヒドとα-ブロモエステルを結合させ、目的のβ-ヒドロキシエステルを良収率で得た。

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