Last Updated:2025/11/25

The neopentyl alcohol undergoes slow nucleophilic substitution at its primary carbon because the bulky tert-butyl group causes severe steric hindrance.

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The neopentyl alcohol undergoes slow nucleophilic substitution at its primary carbon because the bulky tert-butyl group causes severe steric hindrance.

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ネオペンタン由来の脂肪族アルコール((CH3)3C-CH2-OH)は、かさ高いtert-ブチル基が接近を妨げるため、その一次炭素での求核置換反応が遅く進行します。

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