Last Updated:2025/11/21

Researchers conjugated the hapten to keyhole limpet hemocyanin to elicit a strong antibody response, since its large size and distant relation to mammals make the carrier highly antigenic and thus render the hapten immunogenic.

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Researchers conjugated the hapten to keyhole limpet hemocyanin to elicit a strong antibody response, since its large size and distant relation to mammals make the carrier highly antigenic and thus render the hapten immunogenic.

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研究者たちはハプテンをキーホールリンプト由来の大型担体タンパク質(ヘモシアニン)に結合させて強い抗体反応を誘導した。担体が大型で人間や多くの実験動物と系統的に遠いため、担体自体が強い抗原性を示し、ハプテンを免疫原性に変えるからである。

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