that'll do it to you

Phrase

colloquial

(colloquial) That will have that effect on one.

Japanese Meaning

それがあなたに影響を及ぼすだろう / その結果、あなたに効果（影響）が現れるだろう

After pulling two all-nighters in a row, that'll do it to you.

二晩続けて徹夜すると、そういうことになりますよ。

Sense（1）

(colloquial) That will have that effect on one.